Title : Protease-activated receptor 2 induces ROS-mediated inflammation through Akt-mediated NF-κB and FoxO6 modulation during skin photoaging.

Pub. Date : 2021 Aug

PMID : 34082382






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Collectively, our data define that PAR2 induces oxidative stress and inflammation through Akt-mediated phosphorylation of NF-kappaB (Ser536) and FoxO6 (Ser184), which could be a critical upstream regulatory mechanism in ROS-mediated inflammatory response. Reactive Oxygen Species nuclear factor kappa B subunit 1 Homo sapiens