Pub. Date : 2021 Sep
PMID : 34082239
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | When the AhR pathway was activated by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) or 6-formyl (3,2-b) carbazole (FICZ), the migration of U87 cells was inhibited by inducing the expression of a tumor suppressor, IL24, which is a downstream responsive gene of AhR activation. | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |
| 2 | When the AhR pathway was activated by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) or 6-formyl (3,2-b) carbazole (FICZ), the migration of U87 cells was inhibited by inducing the expression of a tumor suppressor, IL24, which is a downstream responsive gene of AhR activation. | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |
| 3 | When the AhR pathway was activated by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) or 6-formyl (3,2-b) carbazole (FICZ), the migration of U87 cells was inhibited by inducing the expression of a tumor suppressor, IL24, which is a downstream responsive gene of AhR activation. | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |
| 4 | When the AhR pathway was activated by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) or 6-formyl (3,2-b) carbazole (FICZ), the migration of U87 cells was inhibited by inducing the expression of a tumor suppressor, IL24, which is a downstream responsive gene of AhR activation. | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |
| 5 | Moreover, a similar AhR-IL24-dependent mechanism for migration inhibition of TCDD was documented in a breast cancer cell line and a lung cancer cell line. | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |
| 6 | This study demonstrated that AhR plays important roles in regulating the migration of glioblastoma, and the induction of the AhR-IL24 axis mediates the inhibition of migration in response to TCDD or FICZ treatment. | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |
| 7 | This study demonstrated that AhR plays important roles in regulating the migration of glioblastoma, and the induction of the AhR-IL24 axis mediates the inhibition of migration in response to TCDD or FICZ treatment. | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |