Title : SARS-CoV-2 Nsp14 activates NF-κB signaling and induces IL-8 upregulation.

Pub. Date : 2021 May 26

PMID : 34075374






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We confirmed the Nsp14-IMPDH2 protein interaction and found that IMPDH2 knockdown or chemical inhibition using ribavirin (RIB) and mycophenolic acid (MPA) abolishes Nsp14-mediated NF-kappaB activation and cytokine induction. Ribavirin inosine monophosphate dehydrogenase 2 Homo sapiens
2 We confirmed the Nsp14-IMPDH2 protein interaction and found that IMPDH2 knockdown or chemical inhibition using ribavirin (RIB) and mycophenolic acid (MPA) abolishes Nsp14-mediated NF-kappaB activation and cytokine induction. Ribavirin inosine monophosphate dehydrogenase 2 Homo sapiens