Pub. Date : 2021 May 12
PMID : 34066157
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We further explored the molecular mechanisms that enables these cells to be primarily resistant to T-DM1 and found that EGFR was activated in the spheroids, leading to an increased HER2 tyrosine phosphorylation. | Tyrosine | epidermal growth factor receptor | Homo sapiens |
| 2 | Blocking EGFR activity by erlotinib reduces HER2 tyrosine phosphorylation and enhances HER2 cell surface expression. | Tyrosine | epidermal growth factor receptor | Homo sapiens |