Title : AICAr, a Widely Used AMPK Activator with Important AMPK-Independent Effects: A Systematic Review.

Pub. Date : 2021 May 4

PMID : 34064363






7 Functional Relationships(s)
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1 AICAr, a Widely Used AMPK Activator with Important AMPK-Independent Effects: A Systematic Review. acadesine protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
2 5-Aminoimidazole-4-carboxamide ribonucleoside (AICAr) has been one of the most commonly used pharmacological modulators of AMPK activity. acadesine protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
3 5-Aminoimidazole-4-carboxamide ribonucleoside (AICAr) has been one of the most commonly used pharmacological modulators of AMPK activity. acadesine protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
4 The majority of early studies on the role of AMPK, both in the physiological regulation of metabolism and in cancer pathogenesis, were based solely on the use of AICAr as an AMPK-activator. acadesine protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
5 The majority of early studies on the role of AMPK, both in the physiological regulation of metabolism and in cancer pathogenesis, were based solely on the use of AICAr as an AMPK-activator. acadesine protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
6 This review aims to give an overview of the present knowledge on AMPK-dependent and AMPK-independent effects of AICAr on metabolism, hypoxia, exercise, nucleotide synthesis, and cancer, calling for caution in the interpretation of AICAr-based studies in the context of understanding AMPK signaling pathway. acadesine protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
7 This review aims to give an overview of the present knowledge on AMPK-dependent and AMPK-independent effects of AICAr on metabolism, hypoxia, exercise, nucleotide synthesis, and cancer, calling for caution in the interpretation of AICAr-based studies in the context of understanding AMPK signaling pathway. acadesine protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens