Pub. Date : 2021 Sep 15
PMID : 34052350
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Anemarrhena Saponins Attenuate Insulin Resistance in Rats with High-Fat Diet-Induced Obesity via the IRS-1/PI3K/AKT Pathway. | Saponins | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 2 | Moreover, anemarrhena saponins up-regulated the phosphorylation levels of IRS-1, PI3K and AKT, promoted insulin signal transduction, and reduced liver injury induced by insulin resistance. | Saponins | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 3 | CONCLUSIONS: These findings suggest that anemarrhena saponins could promote insulin signal transduction through the IRS-1/PI3K/AKT pathway, thereby reducing the damage caused by insulin resistance. | Saponins | AKT serine/threonine kinase 1 | Rattus norvegicus |