Pub. Date : 2021 May 28
PMID : 34050173
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The NAD+-dependent SIRT6 deacylase regulates aging and metabolism through mechanisms that largely remain unknown. | NAD | sirtuin 6 | Mus musculus |
| 2 | To mediate these changes, mechanistically, SIRT6 increases hepatic gluconeogenic gene expression, de novo NAD+ synthesis, and systemically enhances glycerol release from adipose tissue. | NAD | sirtuin 6 | Mus musculus |