Title : Restoration of energy homeostasis by SIRT6 extends healthy lifespan.

Pub. Date : 2021 May 28

PMID : 34050173

2 Functional Relationships(s)
Compound Name
Protein Name
1 The NAD+-dependent SIRT6 deacylase regulates aging and metabolism through mechanisms that largely remain unknown. NAD sirtuin 6 Mus musculus
2 To mediate these changes, mechanistically, SIRT6 increases hepatic gluconeogenic gene expression, de novo NAD+ synthesis, and systemically enhances glycerol release from adipose tissue. NAD sirtuin 6 Mus musculus