Title : Randomized Controlled Trial Substudy of Cell-specific Mechanisms of Janus Kinase 1 Inhibition With Upadacitinib in the Crohn's Disease Intestinal Mucosa: Analysis From the CELEST Study.

Pub. Date : 2021 Nov 15

PMID : 34042156






2 Functional Relationships(s)
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1 Randomized Controlled Trial Substudy of Cell-specific Mechanisms of Janus Kinase 1 Inhibition With Upadacitinib in the Crohn"s Disease Intestinal Mucosa: Analysis From the CELEST Study. upadacitinib Janus kinase 1 Homo sapiens
2 We aimed to provide mechanistic insights into the JAK1-selective inhibitor upadacitinib through a transcriptomics substudy on biopsies from patients with Crohn"s disease from CELEST. upadacitinib Janus kinase 1 Homo sapiens