Title : Fabrication of All-Trans Retinoic Acid loaded Chitosan/Tripolyphosphate Lipid Hybrid Nanoparticles as a Novel Oral Delivery Approach for Management of Diabetic Nephropathy in Rats.

Pub. Date : 2021 Sep

PMID : 34015278






1 Functional Relationships(s)
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1 Treatment with free ATRA and the selected formulations led to a significant amelioration of DN by reducing of creatinine, urea, TNF-alpha, ICAM-1, GM-CSF, VEGF levels as well as elevating AMPK and LKB1 levels. Tretinoin vascular endothelial growth factor A Rattus norvegicus