Pub. Date : 2021 Apr
PMID : 33987364
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, treatment with FA and ICA remarkably down-regulated the serum expression levels of LH, PRL, T, and E2, as well as the mRNA expression levels of ERalpha, PR, ERK1, and ERK2. | icariin | estrogen receptor 1 | Rattus norvegicus |
| 2 | Conclusions: Our outcomes revealed that FA and ICA might potentially inhibit ERalpha, PR, ERK1/2, and their phosphorylated proteins via the ERK signaling pathway, thus indicating a positive feedback control for the degree of breast hyperplasia. | icariin | estrogen receptor 1 | Rattus norvegicus |