Pub. Date : 2022 Jan
PMID : 33971703
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Enrichment of Wee1/CDC2 and NF-kappaB Signaling Pathway Constituents Mutually Contributes to CDDP Resistance in Human Osteosarcoma. | Cisplatin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | Although the Wee1/CDC2 and NF-kappaB pathways were reported to show abnormal activation in some tumor cells with CDDP resistance, whether there is any concrete connection is currently unclear. | Cisplatin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | Conclusion: Simultaneous enrichment of molecules in the Wee1/CDC2 and NF-kappaB pathways and their consequent coactivation is a new molecular mechanism of CDDP resistance in OS cells. | Cisplatin | nuclear factor kappa B subunit 1 | Homo sapiens |