Pub. Date : 2021 Aug
PMID : 33962228
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | LncRNA NEAT1 inhibition upregulates miR-16-5p to restrain the progression of sepsis-induced lung injury via suppressing BRD4 in a mouse model. | mir-16-5p | nuclear paraspeckle assembly transcript 1 (non-protein coding) | Mus musculus |
| 2 | However, the role of nuclear paraspeckle assembly transcript 1 (NEAT1) binding miR-16-5p in sepsis-induced lung injury remains largely unknown. | mir-16-5p | nuclear paraspeckle assembly transcript 1 (non-protein coding) | Mus musculus |
| 3 | We aim to explore the effect of NEAT1 sponging miR-16-5p on sepsis-induced lung injury via regulating bromodomain containing 4 (BRD4). | mir-16-5p | nuclear paraspeckle assembly transcript 1 (non-protein coding) | Mus musculus |
| 4 | NEAT1 bound with miR-16-5p and miR-16-5p targeted BRD4. | mir-16-5p | nuclear paraspeckle assembly transcript 1 (non-protein coding) | Mus musculus |
| 5 | NEAT1 bound with miR-16-5p and miR-16-5p targeted BRD4. | mir-16-5p | nuclear paraspeckle assembly transcript 1 (non-protein coding) | Mus musculus |
| 6 | CONCLUSION: NEAT1 inhibition upregulates miR-16-5p to repress the progression of sepsis-induced lung injury via downregulating BRD4. | mir-16-5p | nuclear paraspeckle assembly transcript 1 (non-protein coding) | Mus musculus |