Title : Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer.

Pub. Date : 2021 Aug

PMID : 33957094






1 Functional Relationships(s)
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1 Herein, we find that NTZ induces mitochondrial damage and mitophagy initiation through PINK1-generated phospho-ubiquitin(pS65-Ub) and autophagy receptor-mediated pathway even in the absence of Atg5/Beclin1. nitazoxanide autophagy related 5 Homo sapiens