Pub. Date : 2021 Jun
PMID : 33955520
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The overexpression of miR-101 also suppressed the expression of the miR-101 target gene, TGF-beta1 type I receptor (TbetaR-I), and thereby impaired TGF-beta1/Smad3 signaling, while the opposite was observed upon miR-101 inhibition. | mir-101 | transforming growth factor beta receptor 1 | Homo sapiens |
| 2 | The overexpression of miR-101 also suppressed the expression of the miR-101 target gene, TGF-beta1 type I receptor (TbetaR-I), and thereby impaired TGF-beta1/Smad3 signaling, while the opposite was observed upon miR-101 inhibition. | mir-101 | transforming growth factor beta receptor 1 | Homo sapiens |
| 3 | The overexpression of miR-101 also suppressed the expression of the miR-101 target gene, TGF-beta1 type I receptor (TbetaR-I), and thereby impaired TGF-beta1/Smad3 signaling, while the opposite was observed upon miR-101 inhibition. | mir-101 | transforming growth factor beta receptor 1 | Homo sapiens |
| 4 | Notably, miR-101 inhibition exerted a less pronounced effect upon EMT-related phenotypes in these TbetaR-I inhibitor-treated HK-2 cells, supporting a model wherein miR-101 inhibits TGF-beta1-induced EMT by suppressing TbetaR-I expression. | mir-101 | transforming growth factor beta receptor 1 | Homo sapiens |
| 5 | Notably, miR-101 inhibition exerted a less pronounced effect upon EMT-related phenotypes in these TbetaR-I inhibitor-treated HK-2 cells, supporting a model wherein miR-101 inhibits TGF-beta1-induced EMT by suppressing TbetaR-I expression. | mir-101 | transforming growth factor beta receptor 1 | Homo sapiens |
| 6 | Notably, miR-101 inhibition exerted a less pronounced effect upon EMT-related phenotypes in these TbetaR-I inhibitor-treated HK-2 cells, supporting a model wherein miR-101 inhibits TGF-beta1-induced EMT by suppressing TbetaR-I expression. | mir-101 | transforming growth factor beta receptor 1 | Homo sapiens |
| 7 | On the whole, the present study demonstrates that miR-101 is capable of inhibiting TGF-beta1-induced tubular EMT by targeting TbetaR-I, suggesting that it may be an important regulator of RIF. | mir-101 | transforming growth factor beta receptor 1 | Homo sapiens |