Title : Exogenous insulin-like growth factor 1 attenuates sevoflurane anesthesia-induced cognitive dysfunction in aged rats.

Pub. Date : 2021 Jun 1

PMID : 33949883






1 Functional Relationships(s)
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1 In aged rats, intravenous injection of IGF-1 alleviated sevoflurane-caused cognitive injuries and elevated TNF- , IL-1beta and IL-6 levels in the plasma and hippocampus and rescued sevoflurane-depressed Akt phosphorylation. Sevoflurane AKT serine/threonine kinase 1 Rattus norvegicus