Title : Metformin ameliorates scleroderma via inhibiting Th17 cells and reducing mTOR-STAT3 signaling in skin fibroblasts.

Pub. Date : 2021 May 4

PMID : 33947424






1 Functional Relationships(s)
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1 These results suggest that metformin treatment has anti-inflammatory effects on lymphocytes via the inhibition of IL-17 and cytokines related to Th17 differentiation, such as IL-1beta, IL-6, and TNF-alpha. Metformin interleukin 17A Mus musculus