Title : SF3B1 mutation in pancreatic cancer contributes to aerobic glycolysis and tumor growth through a PP2A-c-Myc axis.

Pub. Date : 2021 Nov

PMID : 33932092






1 Functional Relationships(s)
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1 Pharmacological activation of PP2A with FTY-720 markedly compromised the growth advantage induced by the SF3B1K700E mutation in vitro and in vivo. Fingolimod Hydrochloride protein phosphatase 2 phosphatase activator Homo sapiens