Pub. Date : 2021
PMID : 33928089
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We show that BMI1 can positively regulate testosterone production. | Testosterone | Bmi1 polycomb ring finger oncogene | Mus musculus |
| 2 | Mechanistically, in addition to its known role in antioxidant activity, we also report that p38 mitogen-activated protein kinase (MAPK) signaling is activated, and testosterone levels reduced, in BMI1-deficient cells; however, the silencing of the p38 MAPK pathway restores testosterone production. | Testosterone | Bmi1 polycomb ring finger oncogene | Mus musculus |
| 3 | Mechanistically, in addition to its known role in antioxidant activity, we also report that p38 mitogen-activated protein kinase (MAPK) signaling is activated, and testosterone levels reduced, in BMI1-deficient cells; however, the silencing of the p38 MAPK pathway restores testosterone production. | Testosterone | Bmi1 polycomb ring finger oncogene | Mus musculus |