PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33928089-5 2021 We show that BMI1 can positively regulate testosterone production. Testosterone 42-54 Bmi1 polycomb ring finger oncogene Mus musculus 13-17 33928089-6 2021 Mechanistically, in addition to its known role in antioxidant activity, we also report that p38 mitogen-activated protein kinase (MAPK) signaling is activated, and testosterone levels reduced, in BMI1-deficient cells; however, the silencing of the p38 MAPK pathway restores testosterone production. Testosterone 164-176 Bmi1 polycomb ring finger oncogene Mus musculus 196-200 33928089-6 2021 Mechanistically, in addition to its known role in antioxidant activity, we also report that p38 mitogen-activated protein kinase (MAPK) signaling is activated, and testosterone levels reduced, in BMI1-deficient cells; however, the silencing of the p38 MAPK pathway restores testosterone production. Testosterone 274-286 Bmi1 polycomb ring finger oncogene Mus musculus 196-200