Title : NEIL1 and NEIL2 Are Recruited as Potential Backup for OGG1 upon OGG1 Depletion or Inhibition by TH5487.

Pub. Date : 2021 Apr 27

PMID : 33925271






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 NEIL1 and NEIL2 Are Recruited as Potential Backup for OGG1 upon OGG1 Depletion or Inhibition by TH5487. TH5487 8-oxoguanine DNA glycosylase Homo sapiens
2 NEIL1 recruitment kinetics and chromatin binding after DNA damage induction increase in cells treated with OGG1 inhibitor TH5487 in a dose-dependent manner, whereas NEIL2 accumulation at DNA damage sites is prolonged following OGG1 inhibition. TH5487 8-oxoguanine DNA glycosylase Homo sapiens
3 NEIL1 recruitment kinetics and chromatin binding after DNA damage induction increase in cells treated with OGG1 inhibitor TH5487 in a dose-dependent manner, whereas NEIL2 accumulation at DNA damage sites is prolonged following OGG1 inhibition. TH5487 8-oxoguanine DNA glycosylase Homo sapiens