Title : Resveratrol Alleviates the Inhibitory Effect of Tunicamycin-Induced Endoplasmic Reticulum Stress on Expression of Genes Involved in Thyroid Hormone Synthesis in FRTL-5 Thyrocytes.

Pub. Date : 2021 Apr 22

PMID : 33922129






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 While treatment of FRTL-5 cells with TM alone (0.1 microg/mL) for 48 h strongly induced the ER stress-sensitive genes heat shock protein family A member 5 (HSPA5) and DNA damage inducible transcript 3 (DDIT3) and repressed NIS, TPO, TG, TSHR, TTF-1, TTF-2 and PAX-8, combined treatment with TM (0.1 microg/mL) and RSV (10 microM) for 48 h attenuated this effect of TM. Tunicamycin DNA-damage inducible transcript 3 Rattus norvegicus
2 While treatment of FRTL-5 cells with TM alone (0.1 microg/mL) for 48 h strongly induced the ER stress-sensitive genes heat shock protein family A member 5 (HSPA5) and DNA damage inducible transcript 3 (DDIT3) and repressed NIS, TPO, TG, TSHR, TTF-1, TTF-2 and PAX-8, combined treatment with TM (0.1 microg/mL) and RSV (10 microM) for 48 h attenuated this effect of TM. Tunicamycin DNA-damage inducible transcript 3 Rattus norvegicus