Title : Release of adenosine-induced immunosuppression: Comprehensive characterization of dual A2A/A2B receptor antagonist.

Pub. Date : 2021 Jul

PMID : 33894488






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 It inhibits cAMP production in human CD4+ cells, CD8+ cells and moDCs, which leads to diminished CREB phosphorylation and restoration of antitumor cytokine production (IL-2, TNFalpha, IL-12) in multiple primary human immune cells. Cyclic AMP CD4 molecule Homo sapiens