Title : Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: The polyG diseases.

Pub. Date : 2021 Jun 2

PMID : 33887199






2 Functional Relationships(s)
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1 Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: the polyG diseases. polyglycine gamma-glutamylcyclotransferase Homo sapiens
2 These results suggest that translation of expanded GGC repeats into a novel and pathogenic polyglycine-containing protein underlies the presence of intranuclear inclusions and neurodegeneration in NIID. polyglycine gamma-glutamylcyclotransferase Homo sapiens