Title : Functional approaches to the study of G-protein-coupled receptors in postmortem brain tissue: [35S]GTPγS binding assays combined with immunoprecipitation.

Pub. Date : 2021 Aug

PMID : 33876404






1 Functional Relationships(s)
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1 In conclusion, [35S]GTPgammaS binding combined with antibody-mediated immunodetection represents an useful method to separately evaluate the functional activity of drugs acting on GPCRs over each Galpha-protein subtype. Guanosine 5'-O-(3-Thiotriphosphate) succinate-CoA ligase GDP/ADP-forming subunit alpha Homo sapiens