Title : O-GlcNAcylation enhances sensitivity to RSL3-induced ferroptosis via the YAP/TFRC pathway in liver cancer.

Pub. Date : 2021 Apr 16

PMID : 33863873






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 O-GlcNAcylation enhances sensitivity to RSL3-induced ferroptosis via the YAP/TFRC pathway in liver cancer. o-glcnacylation Yes1 associated transcriptional regulator Homo sapiens
2 YAP has been reported to play a pivotal role in controlling ferroptotic death, and the expression of YAP is enhanced and stabilized by O-GlcNAcylation. o-glcnacylation Yes1 associated transcriptional regulator Homo sapiens
3 YAP has been reported to play a pivotal role in controlling ferroptotic death, and the expression of YAP is enhanced and stabilized by O-GlcNAcylation. o-glcnacylation Yes1 associated transcriptional regulator Homo sapiens
4 With YAP knockdown or YAP-T241 mutation, the increased sensitivity to ferroptosis induced by O-GlcNAcylation was abolished. o-glcnacylation Yes1 associated transcriptional regulator Homo sapiens
5 With YAP knockdown or YAP-T241 mutation, the increased sensitivity to ferroptosis induced by O-GlcNAcylation was abolished. o-glcnacylation Yes1 associated transcriptional regulator Homo sapiens