Title : Evaluation of Benzamide-Chalcone Derivatives as EGFR/CDK2 Inhibitor: Synthesis, In-Vitro Inhibition, and Molecular Modeling Studies.

Pub. Date : 2022

PMID : 33858315






1 Functional Relationships(s)
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1 Molecular docking reveals involvement of one hydrogen bond with Met793 in binding with EGFR however; it was not stable during simulation and these compounds bind to the receptor mainly via hydrophobic contacts. Hydrogen epidermal growth factor receptor Homo sapiens