Title : Sepsis-induced acute lung injury in young rats is relieved by calycosin through inactivating the HMGB1/MyD88/NF-κB pathway and NLRP3 inflammasome.

Pub. Date : 2021 Jul

PMID : 33857805






2 Functional Relationships(s)
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1 Sepsis-induced acute lung injury in young rats is relieved by calycosin through inactivating the HMGB1/MyD88/NF-kappaB pathway and NLRP3 inflammasome. 7,3'-dihydroxy-4'-methoxyisoflavone high mobility group box 1 Rattus norvegicus
2 CONCLUSION: CAL alleviates sepsis-induced ALI in young rats by inhibiting the HMGB1/MyD88/NF-kappaB pathway and NLRP3 inflammasome activation. 7,3'-dihydroxy-4'-methoxyisoflavone high mobility group box 1 Rattus norvegicus