Pub. Date : 2021 Apr 28
PMID : 33852279
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We report here the design and development of the first amyloid-beta (Abeta)-targeted, blood-brain barrier (BBB) penetrable theranostic Gd(DOTA)-cyanine dyad, which was synthesized by the conjugation of Gd(DOTA) complex and carbazole-based cyanine dye by the copper(I)-catalyzed azide-alkyne cycloaddition click reaction for imaging of Abeta in vivo and ex vivo in AD mouse models. | Azides | amyloid beta (A4) precursor protein | Mus musculus |