Pub. Date : 2021 Apr
PMID : 33851691
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ibrutinib, a first-in-class BTK inhibitor, has been approved for the treatment of several types of B-cell malignancies worldwide. | ibrutinib | Bruton agammaglobulinemia tyrosine kinase | Mus musculus |
| 2 | However, ibrutinib has off-target activities on non-BTK kinase that are related to adverse effects or might translate into clinical limitations. | ibrutinib | Bruton agammaglobulinemia tyrosine kinase | Mus musculus |