Pub. Date : 2021 Jun
PMID : 33850537
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Butylphthalide inhibits nerve cell apoptosis in cerebral infarction rats via the JNK/p38 MAPK signaling pathway. | 3-n-butylphthalide | mitogen-activated protein kinase 8 | Rattus norvegicus |
| 2 | The aim of the present study was to investigate the influence of butylphthalide on nerve cell apoptosis in rats with cerebral infarction through the c-Jun N-terminal kinase (JNK)/p38 mitogen-activated protein kinase (MAPK) signaling pathway. | 3-n-butylphthalide | mitogen-activated protein kinase 8 | Rattus norvegicus |
| 3 | The aim of the present study was to investigate the influence of butylphthalide on nerve cell apoptosis in rats with cerebral infarction through the c-Jun N-terminal kinase (JNK)/p38 mitogen-activated protein kinase (MAPK) signaling pathway. | 3-n-butylphthalide | mitogen-activated protein kinase 8 | Rattus norvegicus |
| 4 | The model group and the butylphthalide group had markedly higher relative protein expression levels of p-JNK and p-p38 MAPK than the sham-operation group (P<0.05), and the butylphthalide group displayed notably lower relative protein expression levels of p-JNK and p-p38 MAPK than the model group (P<0.05). | 3-n-butylphthalide | mitogen-activated protein kinase 8 | Rattus norvegicus |
| 5 | The model group and the butylphthalide group had markedly higher relative protein expression levels of p-JNK and p-p38 MAPK than the sham-operation group (P<0.05), and the butylphthalide group displayed notably lower relative protein expression levels of p-JNK and p-p38 MAPK than the model group (P<0.05). | 3-n-butylphthalide | mitogen-activated protein kinase 8 | Rattus norvegicus |
| 6 | The model group and the butylphthalide group had markedly higher relative protein expression levels of p-JNK and p-p38 MAPK than the sham-operation group (P<0.05), and the butylphthalide group displayed notably lower relative protein expression levels of p-JNK and p-p38 MAPK than the model group (P<0.05). | 3-n-butylphthalide | mitogen-activated protein kinase 8 | Rattus norvegicus |
| 7 | In conclusion, butylphthalide may inhibit nerve cell apoptosis in rats with cerebral infarction to exert a protective effect, which may be associated with the JNK/p38 MAPK signaling pathway. | 3-n-butylphthalide | mitogen-activated protein kinase 8 | Rattus norvegicus |