Title : Deciphering the mechanisms of CC-122 resistance in DLBCL via a genome-wide CRISPR screen.

Pub. Date : 2021 Apr 13

PMID : 33847741






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mechanistically, CC-122 induces the degradation of IKZF1/3, leading to T-cell activation and robust cell-autonomous killing in DLBCL. 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione IKAROS family zinc finger 1 Homo sapiens