Title : Systemic toxicities of trastuzumab-emtansine predict tumor response in HER2+ metastatic breast cancer.

Pub. Date : 2021 Apr 12

PMID : 33844843






2 Functional Relationships(s)
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1 Systemic toxicities of trastuzumab-emtansine predict tumor response in HER2+ metastatic breast cancer. Maytansine erb-b2 receptor tyrosine kinase 2 Homo sapiens
2 We hypothesized that the systemic toxicities from T-DM1 may have been caused by the free and active maytansine released from the lysed HER2+ tumor cells, and if so, they may correlate with the response to treatment and eventually disease-free survival or patient outcome. Maytansine erb-b2 receptor tyrosine kinase 2 Homo sapiens