Title : IRE1α-XBP1 Affects the Mitochondrial Function of Aβ25-35-Treated SH-SY5Y Cells by Regulating Mitochondria-Associated Endoplasmic Reticulum Membranes.

Pub. Date : 2021

PMID : 33841100






1 Functional Relationships(s)
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1 Increased levels of ATP, restoration of mitochondrial membrane potential, and decreased production of mitochondrial reactive oxygen species after Abeta treatment in the presence of 4mu8c showed that inhibiting the IRE1alpha-XBP1 axis effectively mitigated Abeta-induced mitochondrial dysfunction in SH-SY5Y cells. Adenosine Triphosphate endoplasmic reticulum to nucleus signaling 1 Homo sapiens