Title : Combating drug resistance in acute myeloid leukaemia by drug rotations: the effects of quizartinib and pexidartinib.

Pub. Date : 2021 Apr 8

PMID : 33832508






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The gatekeeper mutation F691L confers resistance to specific FLT3 inhibitors such as quizartinib, but pexidartinib is much less resistance to this mutation. pexidartinib fms related receptor tyrosine kinase 3 Homo sapiens