Pub. Date : 2021 Jun
PMID : 33812059
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The Mediator complex kinase module is necessary for fructose regulation of liver glycogen levels through induction of glucose-6-phosphatase catalytic subunit (G6pc). | Glycogen | glucose-6-phosphatase, catalytic | Mus musculus |
| 2 | The Mediator complex kinase module is necessary for fructose regulation of liver glycogen levels through induction of glucose-6-phosphatase catalytic subunit (G6pc). | Glycogen | glucose-6-phosphatase, catalytic | Mus musculus |
| 3 | However, feeding in the presence of fructose in water suppressed glycogen accumulation in the liver by up-regulating the expression of glucose-6-phosphatase catalytic subunit (G6pc) gene although the exact mechanism is unknown. | Glycogen | glucose-6-phosphatase, catalytic | Mus musculus |
| 4 | However, feeding in the presence of fructose in water suppressed glycogen accumulation in the liver by up-regulating the expression of glucose-6-phosphatase catalytic subunit (G6pc) gene although the exact mechanism is unknown. | Glycogen | glucose-6-phosphatase, catalytic | Mus musculus |
| 5 | CONCLUSIONS: Taken together, our data suggest that the kinase module of the Mediator complex is necessary for the transcriptional activation of metabolic genes, such as G6pc, and has an important role in regulation of the glycogen levels in the liver through altering transcription factor binding and activity at the G6pc promoter. | Glycogen | glucose-6-phosphatase, catalytic | Mus musculus |
| 6 | CONCLUSIONS: Taken together, our data suggest that the kinase module of the Mediator complex is necessary for the transcriptional activation of metabolic genes, such as G6pc, and has an important role in regulation of the glycogen levels in the liver through altering transcription factor binding and activity at the G6pc promoter. | Glycogen | glucose-6-phosphatase, catalytic | Mus musculus |