| Protein Name | glucose-6-phosphatase catalytic subunit 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 14377 |
| Gene Symbol | G6pc1 |
| UniProt | P35576 (G6PC1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
222
Total Number of Articles : 313 |
Description |
glucose-6-phosphatase catalytic subunit 1 |
| Gene Summary |
The enzyme encoded by this gene is a multisubunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for glucose-6-phosphate, inorganic phosphate, and glucose. This gene is one of three glucose-6-phosphatase catalytic-subunit-encoding genes in mouse. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). [provided by RefSeq, Sep 2015] |
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