Pub. Date : 2021 Mar 22
PMID : 33810046
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Multifunctional Tyrosinase Inhibitor Peptides with Copper Chelating, UV-Absorption and Antioxidant Activities: Kinetic and Docking Studies. | Copper | tyrosinase | Homo sapiens |
| 2 | DIP1 was found to be the most potent tyrosinase inhibitor (IC50 = 3.04 +- 0.39 mM), which could be due to the binding interactions between its aromatic amino acid residues (Y2 and D7) with tyrosinase hotspots (H85, V248, H258, H263, F264, R268, V283 and E322) and its ability to chelate copper ion within the substrate-binding pocket. | Copper | tyrosinase | Homo sapiens |