Title : Hypoxia via ERK Signaling Inhibits Hepatic PPARα to Promote Fatty Liver.

Pub. Date : 2021

PMID : 33798787






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 During fasting, fatty acid beta-oxidation is induced by PPARalpha, and refeeding inhibits beta-oxidation. Fatty Acids peroxisome proliferator activated receptor alpha Mus musculus
2 CONCLUSIONS: Overall, our results demonstrate that ERK activated by hypoxia signaling plays a crucial role in fatty acid beta-oxidation genes by repressing hepatocyte PPARalpha signaling. Fatty Acids peroxisome proliferator activated receptor alpha Mus musculus