Pub. Date : 2021 May 1
PMID : 33775688
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Since NF-kappaB activity is considered to be relatively high in particular when it comes to breast cancer, in the present work, we proposed that the inhibition of NF-kappaB activity can augment and enhance the sensitivity of breast cancer cells to chemotherapy such as doxorubicin (DOX) by virtue of MDR modulation. | Doxorubicin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | Since NF-kappaB activity is considered to be relatively high in particular when it comes to breast cancer, in the present work, we proposed that the inhibition of NF-kappaB activity can augment and enhance the sensitivity of breast cancer cells to chemotherapy such as doxorubicin (DOX) by virtue of MDR modulation. | Doxorubicin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | Since NF-kappaB activity is considered to be relatively high in particular when it comes to breast cancer, in the present work, we proposed that the inhibition of NF-kappaB activity can augment and enhance the sensitivity of breast cancer cells to chemotherapy such as doxorubicin (DOX) by virtue of MDR modulation. | Doxorubicin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 4 | Since NF-kappaB activity is considered to be relatively high in particular when it comes to breast cancer, in the present work, we proposed that the inhibition of NF-kappaB activity can augment and enhance the sensitivity of breast cancer cells to chemotherapy such as doxorubicin (DOX) by virtue of MDR modulation. | Doxorubicin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 5 | Our results demonstrated that the DOX-resistant MCF-7 and MDA-MB-231 clones exhibit higher NF-kappaB (p65) function, which is linked to the upregulated expression of ABCB1 and ABCC1 transporter proteins. | Doxorubicin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 6 | The DOX/NF-kappaB inhibitor combinations hampered NF-kappaB (p65) activation and downregulated MDR efflux transporters" level. | Doxorubicin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 7 | The DOX/NF-kappaB inhibitor combinations hampered NF-kappaB (p65) activation and downregulated MDR efflux transporters" level. | Doxorubicin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 8 | Breast cancer cell migration was sharply suppressed in cells co-treated with DOX/NF-kappaB inhibitors. | Doxorubicin | nuclear factor kappa B subunit 1 | Homo sapiens |