Pub. Date : 2021 Aug 18
PMID : 33758937
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Programmed cell death 1 (PD-1) prompts FoxP3 in Tregs expression and enhances the suppressive activity of Tregs. | tregs | programmed cell death 1 | Homo sapiens |
| 2 | Programmed cell death 1 (PD-1) prompts FoxP3 in Tregs expression and enhances the suppressive activity of Tregs. | tregs | programmed cell death 1 | Homo sapiens |
| 3 | OBJECTIVE: To evaluate the role of PD-1 in Tregs function and triiodothyronine (T3) in PD-1 expression in patients with GD and mice treated with T3. | tregs | programmed cell death 1 | Homo sapiens |
| 4 | RESULTS: PD-1 expression in Tregs and the suppressive function of Tregs significantly decreased in patients with GD. | tregs | programmed cell death 1 | Homo sapiens |
| 5 | T3 reduced PD-1 expression in human Tregs in a concentration- and time-dependent manner in vitro. | tregs | programmed cell death 1 | Homo sapiens |
| 6 | CONCLUSIONS: Tregs dysfunction in GD patients might be due to down-regulation of PD-1 expression in Tregs induced by high levels of serum T3. | tregs | programmed cell death 1 | Homo sapiens |
| 7 | CONCLUSIONS: Tregs dysfunction in GD patients might be due to down-regulation of PD-1 expression in Tregs induced by high levels of serum T3. | tregs | programmed cell death 1 | Homo sapiens |