Title : Use of C. elegans as a 3R-compliant in vivo model for the chemoprevention of cisplatin-induced neurotoxicity.

Pub. Date : 2021 Jul

PMID : 33753139






1 Functional Relationships(s)
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1 CisPt causes glutathione (GSH) depletion and RNAi-mediated knockdown of the glutamate-cysteine ligase GCS-1 aggravates the CisPt-induced inhibition of pharyngeal pumping. Cisplatin Glutamate--cysteine ligase Caenorhabditis elegans