Title : Combination Chemo-Immunotherapy for Pancreatic Cancer Using the Immunogenic Effects of an Irinotecan Silicasome Nanocarrier Plus Anti-PD-1.

Pub. Date : 2021 Mar

PMID : 33747719






1 Functional Relationships(s)
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1 It is demonstrated that improved irinotecan delivery by a lipid bilayer coated mesoporous silica nanoparticle, also known as a silicasome, can improve PDAC survival through a chemo-immunotherapy response in an orthotopic Kras-dependent pancreatic cancer model. mesoporous silica KRAS proto-oncogene, GTPase Homo sapiens