Title : Activation of ATF4 triggers trabecular meshwork cell dysfunction and apoptosis in POAG.

Pub. Date : 2021 Mar 10

PMID : 33714955






2 Functional Relationships(s)
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1 In this study, we demonstrated that the eIF2-alpha/ATF4/CHOP branch of unfolded protein response (UPR) was activated in human trabecular meshwork cells (HTMCs) upon tert-butyl hydroperoxide (TBHP) exposure. tert-Butylhydroperoxide eukaryotic translation initiation factor 2A Homo sapiens
2 In this study, we demonstrated that the eIF2-alpha/ATF4/CHOP branch of unfolded protein response (UPR) was activated in human trabecular meshwork cells (HTMCs) upon tert-butyl hydroperoxide (TBHP) exposure. tert-Butylhydroperoxide eukaryotic translation initiation factor 2A Homo sapiens