Pub. Date : 2021
PMID : 33681192
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Only bone morphogenetic protein 4 (Bmp4), a key molecule regulating UB branching, is significantly downregulated in Rik PB/PB embryonic kidney, while the expression levels of other molecules involved in the regulation of UB branching were not significantly different according to the RNA-sequencing (RNA-seq) data, and the results were verified by quantitative real-time polymerase chain reaction (RT-PCR) and immunofluorescence assays. | BM | bone morphogenetic protein 4 | Mus musculus |
| 2 | Only bone morphogenetic protein 4 (Bmp4), a key molecule regulating UB branching, is significantly downregulated in Rik PB/PB embryonic kidney, while the expression levels of other molecules involved in the regulation of UB branching were not significantly different according to the RNA-sequencing (RNA-seq) data, and the results were verified by quantitative real-time polymerase chain reaction (RT-PCR) and immunofluorescence assays. | BM | bone morphogenetic protein 4 | Mus musculus |
| 3 | Only bone morphogenetic protein 4 (Bmp4), a key molecule regulating UB branching, is significantly downregulated in Rik PB/PB embryonic kidney, while the expression levels of other molecules involved in the regulation of UB branching were not significantly different according to the RNA-sequencing (RNA-seq) data, and the results were verified by quantitative real-time polymerase chain reaction (RT-PCR) and immunofluorescence assays. | BM | bone morphogenetic protein 4 | Mus musculus |
| 4 | These findings suggest that abnormal expression of Rik may cause a reduction in the UB branches by reducing the expression levels of the UB branching-related molecule Bmp4, thus leading to the development of CAKUT. | BM | bone morphogenetic protein 4 | Mus musculus |
| 5 | These findings suggest that abnormal expression of Rik may cause a reduction in the UB branches by reducing the expression levels of the UB branching-related molecule Bmp4, thus leading to the development of CAKUT. | BM | bone morphogenetic protein 4 | Mus musculus |