Pub. Date : 2021 Mar 7
PMID : 33678162
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CONCLUSION: Our findings indicate that pathogenic E. coli HPI infection of Saba pigs causes pyroptosis of macrophages characterized by upregulated expression of pyroptosis key factors in the NLRP3/ASC/caspase-1 signaling pathway, direct cell membrane pore formation, and secretion of the inflammatory factor IL-1beta and IL-18 downstream of NLRP3 and caspase-1 activation to enhance the inflammatory response. | 3-(2-(4-azidobenzamidino)ethyl)-5-hydroxyindole | interleukin 1 alpha | Sus scrofa |