Title : IL-10 derived from Hepatocarcinoma cells improves human induced regulatory T cells function via JAK1/STAT5 pathway in tumor microenvironment.

Pub. Date : 2021 May

PMID : 33667986






1 Functional Relationships(s)
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1 Our results suggest that improved stability and abnormal accumulation of Tregs in tumor microenvironment is IL-10/JAK1/STAT5 signal pathway-dependent and provide a novel approach for improving the efficiency of anti-tumor immunotherapy. tregs signal transducer and activator of transcription 5A Homo sapiens