Pub. Date : 2021 Jun 1
PMID : 33652071
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | These findings indicate that CYP3A5, CYP3A4, CYP2C8 and CYP2C9 play a major role in the transformation of carfentanil to M1 (norcarfentanil), M11, M13 and M15 through N-dealkylation of piperidine ring, hydroxylation of phenethyl group and ketone formation on phenethyl linker by human liver micrsomes. | Norcarfentanil | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |