Pub. Date : 2021 Aug
PMID : 33649523
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The heterozygous genotype of CYP3A4*22 showed a trend of association with skin reactions in pts treated with paclitaxel and nab-paclitaxel (RR = 6.92; 95% CI 0.47, 99.8; p = 0.0766). | Paclitaxel | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | The heterozygous genotype of CYP3A4*22 showed a trend of association with skin reactions in pts treated with paclitaxel and nab-paclitaxel (RR = 6.92; 95% CI 0.47, 99.8; p = 0.0766). | Paclitaxel | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 3 | Despite the population was heterogeneous, CYP3A4*22 and CYP2C8 SNPs may influence paclitaxel and nab-paclitaxel toxicity and ABCB1 c.3435 may affect taxanes effectiveness, even if any statistically significant was found. | Paclitaxel | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 4 | Despite the population was heterogeneous, CYP3A4*22 and CYP2C8 SNPs may influence paclitaxel and nab-paclitaxel toxicity and ABCB1 c.3435 may affect taxanes effectiveness, even if any statistically significant was found. | Paclitaxel | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |