Title : Endogenous SO2-dependent Smad3 redox modification controls vascular remodeling.

Pub. Date : 2021 May

PMID : 33647858






1 Functional Relationships(s)
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1 Sulfenylation of Smad3 at cysteine-64 inhibits its DNA binding activity, while mutation of this site attenuates the protective effects of SO2 on angiotensin II-induced vascular remodeling and hypertension. Sulfur Dioxide angiotensinogen Homo sapiens