Pub. Date : 2021 Aug
PMID : 33635721
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Folic acid ameliorates neonatal isolation-induced autistic like behaviors in rats: Epigenetic modifications of BDNF and GFAP promotors". | Folic Acid | brain-derived neurotrophic factor | Rattus norvegicus |
| 2 | Folic acid administration concurrently with isolation, reduced neonatal isolation-induced autistic-like behaviors, decreased oxidative stress, regained BDNF and GFAP gene methylation, ameliorated structural changes in the frontal cortices of isolated folic acid treated rats. | Folic Acid | brain-derived neurotrophic factor | Rattus norvegicus |
| 3 | Molecular and biochemical analyses showed that -NI induces DNA hypomethylation of BDNF and GFAP, increased oxidative stress markers, and neuroinflammation -All of these changes were reversed by daily folic acid supplementation. | Folic Acid | brain-derived neurotrophic factor | Rattus norvegicus |